CONTACT INFORMATION
Professor: Mary L. Kraft
University of Illinois
600 S Mathews Ave
208 RAL, MC-712
Urbana, IL 61801
phone: 217-333-2228
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publications
  1. Melanie A. Brunet and Mary L. Kraft."Toward Understanding the Subcellular Distributions of Cholesterol and Sphingolipids Using High-Resolution NanoSIMS Imaging," Accounts of Chemical Research 2023, 56 (7), 752-762. DOI: 10.1021/acs.accounts.2c00760. 
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  2. Melanie A. Brunet, Brittney L. Gorman and Mary L. Kraft. "Depth Correction of 3D NanoSIMS Images Shows Intracellular Lipid and Cholesterol Distributions while Capturing the Effects of Differential Sputter Rate," ACS Nano 2022, 16 (10), 16221-16233. DOI: 10.1021/acsnano.2c05148.
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  3. Isamar Pastrana-Otero, Sayani Majumdar, Aidan E. Gilchrist, Brendan A. C. Harley and Mary L. Kraft. "Identification of the Differentiation Stages of Living Cells from the Six Most Immature Murine Hematopoietic Cell Populations by Multivariate Analysis of Single-Cell Raman Spectra," Analytical Chemistry 2022, 94 (35), 11999-12007. DOI: 10.1021/acs.analchem.2c00714.
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  4. Brittney L. Gorman, Melanie A. Brunet and Mary L. Kraft. "Depth correction of 3D NanoSIMS images using secondary electron pixel intensity," Biointerphases, 2021, 16 (4), 041005. DOI: 10.1116/6.0001092.
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  5. Isamar Pastrana-Otero, Sayani Majumdar, Aidan E. Gilchrist, Brittney L. Gorman, Brendan A. C. Harley and Mary L. Kraft . "Development of an inexpensive Raman-compatible substrate for the construction of a microarray screening platform," Analyst, 2020, 145, 7030-7039. DOI: 10.1039/d0an01153c.
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  6. Sayani Majumdar and Mary L. Kraft. "Exploring the maturation of a monocytic cell line using self-organizing maps of single-cell Raman spectra," Biointerphases, 2020, 15, 041010. DOI: 10.1116/6.0000363.
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  7. Brittney L. Gorman, Melanie A. Brunet, Susan N. Pham and Mary L. Kraft. "Measurement of Absolute Concentration at the Subcellular Scale," ACS Nano, 2020, 14 (6), 6414-6419. DOI: 10.1021/acsnano.0c04285.
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  8. Brittney L. Gorman and Mary L. Kraft. "High-Resolution Secondary Ion Mass Spectrometry Analysis of Cell Membranes," Analytical Chemistry, 2020, 92 (2), 1645-1652. DOI: 10.1021/acs.analchem.9b04492.
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  9. Brittney L. Gorman, Ashley N. Yeager, Corryn E. Chini and Mary L. Kraft. "Imaging the distributions of lipids and proteins in the plasma membrane with high-resolution secondary ion mass spectrometry," in Characterization of Biological Membranes: Structure and Dynamics; Eds.: Nieh, M.-P.; Heberle, F. A.; Katsaras, J.; De Gruyter: Berlin, Boston. 2019; Chapter 9, 287-322. DOI:10.1515/9783110544657-009.
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  10. Ji Sun Choi, Yelena Ilin, Mary L. Kraft and Brendan A. C. Harley. "Tracing Hematopoietic Progenitor Cell Neutrophilic Differentiation via Raman Spectroscopy," Bioconjugate Chemistry, 2018, 29 (9), 3121-3128. DOI: https://doi.org/10.1021/acs.bioconjchem.8b00459.
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  11. Ashley N. Yeager, Peter K. Weber and Mary L. Kraft. "Cholesterol is enriched in the sphingolipid patches on the substrate near nonpolarized MDCK cells, but not in the sphingolipid domains in their plasma membranes," Biochimica et Biophysica Acta, Biomembranes, 2018, 1860 (10), 2004-2011. DOI:10.1016/j.bbamem.2018.04.008.
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  12. Vahid Mirshafiee, Brendan A. C. Harley and Mary L. Kraft. "Visualizing Intra-Population Hematopoietic Cell Heterogeneity with Self-Organizing Maps of SIMS Data," Tissue Engineering Part C: Methods, 2018, 24 (6), 322 - 330. DOI:10.1089/ten.TEC.2017.0382.
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  13. Corryn E. Chini, Gregory L. Fisher, Ben Johnson, Michael M. Tamkun and Mary L. Kraft. "Observation of endoplasmic reticulum tubules via TOF-SIMS tandem mass spectrometry imaging of transfected cells," Biointerphases 2018, 13 (3), 03B409. DOI: 10.1116/1.5019736.
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  14. Mary L. Kraft. "Sphingolipid Organization in the Plasma Membrane and the Mechanisms That Influence It," Frontiers in Cell and Developmental Biology, 2017, 4 (154), DOI: 10.3389/fcell.2016.00154.
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  15. Ashley N. Yeager, Peter K. Weber and Mary L. Kraft. "Three-dimensional imaging of cholesterol and sphingolipids within a Madin-Darby canine kidney cell," Biointerphases, 2016, 11 (2), 02A309. DOI: 10.1116/1.4939681.
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  16. Vahid Mirshafiee, Raehyun Kim, Morteza Mahmoudi and Mary L. Kraft. "The importance of selecting a proper biological milieu for protein corona analysis in vitro: Human plasma vs. human serum," The International Journal of Biochemistry & Cell Biology, 2016, 75, 188-195. DOI: 10.1016/j.biocel.2015.11.019.
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  17. Vahid Mirshafiee,* Raehyun Kim, Soyun Park, Morteza Mahmoudi and Mary L. Kraft. "Impact of protein pre-coating on the protein corona composition and nanoparticle cellular uptake", Biomaterials, 2016, 75, 295-304. DOI: 10.1016/j.biomaterials.2015.10.019. *VM and RK contributed equally to this work.
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  18. Yelena Ilin, Ji Sun Choi, Brendan A. C. Harley and Mary L. Kraft. "Identifying states along the hematopoietic stem cell differentiation hierarchy with single cell specificity via Raman spectroscopy," Analytical Chemistry, 2015 87 (22), 11317-11324. DOI: 10.1021/acs.analchem.5b02537.
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  19. Robert L. Wilson, Jessica F. Frisz, Haley A. Klitzing, Joshua Zimmerberg, Peter K. Weber and Mary L. Kraft. "Hemagglutinin clusters in the plasma membrane are not enriched with cholesterol and sphingolipids," Biophysical Journal, 2015, 108 (7), 1652-1659, DOI: 10.1016/j.bpj.2015.02.026.
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  20. Yelena Ilin and Mary L. Kraft. "Secondary ion mass spectrometry and Raman spectroscopy for tissue engineering applications," Current Opinion in Biotechnology, 2015, 31, 108-116, doi: 10.1016/j.copbio.2014.10.011.
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  21. Mary L. Kraft and Haley A. Klitzing. "Imaging Lipids with Secondary Ion Mass Spectrometry," Biochimica et Biophysica Acta, Molecular and Cell Biology of Lipids, 2014, 1841 (8), 1108-1119, DOI: 10.1016/j.bbalip.2014.03.003.
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  22. Yelena Ilin and Mary L. Kraft. "Identifying the lineages of individual cells in cocultures by multivariate analysis of Raman spectra," Analyst, 2014, 139, 2177-2185, DOI: 10.1039/c3an02156d.
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  23. Mary L. Kraft. "Plasma membrane organization and function: moving past lipid rafts," Molecular Biology of the Cell, 2013, 24 (18), 2765-2768, doi: 10.1091/mbc.E13-03-0165.
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  24. Jessica F. Frisz, Haley A. Klitzing, Kaiyan Lou, Ian D. Hutcheon, Peter K. Weber, Joshua Zimmerberg and Mary L. Kraft. "Sphingolipid Domains in the Plasma Membranes of Fibroblasts are Not Enriched with Cholesterol," Journal of Biological Chemistry, 2013, 288, 16855-16861, doi: 10.1074/jbc.M113.473207.
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  25. Vahid Mirshafiee, Morteza Mahmoudi, Kaiyan Lou, Jianjun Cheng and Mary L. Kraft. "Protein Corona Significantly Reduces Active Targeting Yield," Chemical Communications, 2013, 49 (25), 2557-2559, DOI: 10.1039/C3CC37307J.
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  26. Jessica F. Frisz,* Kaiyan Lou,* Haley A. Klitzing, William P. Hanafin, Vladimir Lizunov, Robert L. Wilson, Kevin J. Carpenter, Raehyun Kim, Ian D. Hutcheon, Joshua Zimmerberg, Peter K. Weber and Mary L. Kraft. "Direct chemical evidence for sphingolipid domains in the plasma membranes of fibroblasts," Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (8), E613-E622, DOI: 10.1073/pnas.1216585110. *JFF and KL contributed equally to this work.
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  27. Robert L. Wilson and Mary L. Kraft. "Quantifying the Molar Percentages of Cholesterol in Supported Lipid Membranes by Time-of-Flight Secondary Ion Mass Spectrometry and Multivariate Analysis," Analytical Chemistry, 2013, 85 (1), 91-97, DOI: 10.1021/ac301856z.
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  28. Raehyun Kim,* Kaiyan Lou* and Mary L. Kraft. "A new long wavelength borondipyrromethene (BODIPY) sphingosine for studying sphingolipid dynamics in live cells," Journal of Lipid Research, 2013, 54 (1), 265-275, DOI: 10.1194/jlr.D029207. *RK and KL contributed equally to this work.
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  29. Haley A. Klitzing, Peter K. Weber and Mary L. Kraft. “Secondary ion mass spectrometry imaging of biological membranes at high spatial resolution,” in “Nanoimaging: Methods and Protocols; Eds.: A. A. Sousa and M. J. Kruhlak; Humana Press: Totowa, New Jersey. 2013; Vol. 950, Chapter 26, 483-501.
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  30. Jessica F. Frisz, Ji Sun Choi, Robert L. Wilson, Brendan A. C. Harley and Mary L. Kraft. "Identifying the Differentiation Stage of Individual Primary Hematopoietic Cells from Mouse Bone Marrow by Multivariate Analysis of TOF-Secondary Ion Mass Spectrometry Data," Analytical Chemistry, 2012, 84 (10), 4307-4313, DOI:10.1021/ac203329j.
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  31. Robert L. Wilson, Jessica F. Frisz, William P. Hanafin, Kevin J. Carpenter, Ian D. Hutcheon, Peter K. Weber and Mary L. Kraft. "Fluorinated colloidal gold immunolabels for imaging select proteins in parallel with lipids using high-resolution secondary ion mass spectrometry," Bioconjugate Chemistry, 2012, 23 (3), 450-460, DOI:10.1021/bc200482z.
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  32. Christopher R. Anderton, Bita Vaezian, Kaiyan Lou and Mary L. Kraft. "Identification of a lipid-related peak set to enhance the interpretation of TOF-SIMS data from model and cellular membranes," Surface and Interface Analysis, 2012, 44 (3), 322-333, DOI: 10.1002/sia.3806.
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  33. Vladimir Lizunov, Petr Chlanda, Mary L. Kraft and Joshua Zimmerberg. "Long, Saturated Chains: Tasty Domains for Kinases of Insulin Resistance," Developmental Cell, 2011, 21 (4), 604-606, DOI:10.1016/j.devcel.2011.10.001.
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  34. Christopher R. Anderton, Peter K. Weber, Kaiyan Lou, Ian D. Hutcheon and Mary L. Kraft. "Correlated AFM and NanoSIMS imaging to probe cholesterol-induced changes in phase behavior and non-ideal mixing in ternary lipid membranes,” Biochimica et Biophysica Acta, Biomembranes, 2011, 1808 (1), 307-315, DOI:10.1016/j.bbamem.2010.09.016.
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  35. Bita Vaezian, Christopher R. Anderton and Mary L. Kraft. "Discriminating and Imaging Different Phosphatidylcholine Species within Phase-Separated Model Membranes by Principal Component Analysis of TOF-Secondary Ion Mass Spectrometry Images,” Analytical Chemistry, 2010, 82 (24), 10006-10014, DOI:10.1021/ac101640c.
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  36. Steven G. Boxer, Mary L. Kraft and Peter K. Weber. Advances in secondary ion mass spectrometry applied to biological samples,” Annual Review of Biophysics, 2009, 38, 53-74, DOI:10.1146/annurev.biophys.050708.133634.
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  37. Jeffrey S. Moore and Mary L. Kraft. Synchronized self-assembly, Science 2008, 320 (5876), 620-621, DOI:10.1126/science.1157225.
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  38. Mary L. Kraft, Peter K. Weber, Marjorie L. Longo, Ian D. Hutcheon and Steven G. Boxer. Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry, Science, 2006, 313, 1948-1951, DOI:10.1126/science.1130279. Highlighted in: Science, Chemical & Engineering News, and Nature Nanotechnology.
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  39. Mary L. Kraft, Simon F. Fishel, Carine Galli Marxer, Peter K. Weber, Ian D. Hutcheon and Steven G. Boxer. Quantitative analysis of supported membrane composition using the NanoSIMS, Applied Surface Science, 2006, 252 (19), 6950-6956, DOI:10.1016/j.apsusc.2006.02.116.
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  40. Carine Galli Marxer, Mary L. Kraft, Peter K. Weber, Ian D. Hutcheon and Steven G. Boxer. Supported membrane composition analysis by secondary ion mass spectrometry with high lateral resolution, Biophysical Journal, 2005, 88 (4), 2965-2975, DOI:10.1529/biophysj.104.057257.
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  41. Chiaki Yoshina-Ishii, Gregory P. Miller, Mary L. Kraft, Eric T. Kool and Steven G. Boxer. General method for modification of liposomes for encoded assembly on supported bilayers, Journal of the American Chemical Society, 2005127 (5), 1356-1357, DOI:10.1021/ja043299k.
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  42. Mary L. Kraft and Jeffrey S. Moore. Multitechnique characterization of fatty acid-modified microgels, Langmuir, 2004, 20 (4), 1111-1119, DOI:10.1021/la035617j.
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  43. Mary L. Kraft and Jeffrey S. Moore. n-Alkyl fatty acid-modified microgels: ion permeation as a function of chain length, Langmuir, 2003, 19 (3), 910-915, DOI:10.1021/la0266637.
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  44. Mary L. Kraft, Scott J. Robinson and Jeffrey S. Moore. Fatty acid-modified microgels: transmission electron microscopy study, Surface and Interface Analysis, 2003, 35 (13), 1065-1068, DOI:10.1002/sia.1644.
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  45. Kyle N. Plunkett, Mary L. Kraft, Qing Yu and Jeffrey S. Moore. Swelling kinetics of disulfide crosslinked microgels, Macromolecules, 2003, 36 (11), 3960-3966, DOI:10.1021/ma025874f.
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  46. Mary L. Kraft and Jeffrey S. Moore. Surfactant-induced lysis of lipid-modified microgels, Journal of the American Chemical Society, 2001, 123 (51), 12921-12922, DOI:10.1021/ja016975g.
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  47. David J. Beebe, Heffrey S. Moore, Qing Yu, Robin H. Liu, Mary L. Kraft, Byung-Ho Jo and Chelladurai Devadoss. Microfluidic tectonics: A comprehensive platform for microfluidic systems, Proceedings of the National Academy of Sciences of the United States of America, 2000, 97 (25), 13488-13493, DOI:10.1073/pnas.250273097.

Contributions to Scientific Newsletters

  1. Mary L. Kraft and Raehyun Kim. "Our evolving view of plasma membrane domains" ASBMB Today, 2014, 13 (8), 20 - 21.